Current Concepts in Anabolic-Androgenic SteroidsAnabolic-androgenic steroids AAS are synthetic derivatives of testosterone. According to surveys and media reports, the legal and illegal use of these drugs is gaining popularity. Testosterone restores sex drive and boosts muscle mass, making it central to 2 of society's rising preoccupations: The anabolic effects of AAS have been questioned proteina anabolic monster whey decades, but anabolic androgenic steroids pdf scientific investigation of supraphysiologic doses supports the efficacy of these regimens. Testosterone has potent anabolic effects on the anabolic androgenic steroids pdf system, including an increase in lean body mass, a dose-related hypertrophy of muscle fibers, and an increase anabolic androgenic steroids pdf muscle strength.
Anabolic-androgenic steroids AAS are synthetic derivatives of testosterone. According to surveys and media reports, the legal and illegal use of these drugs is gaining popularity. Testosterone restores sex drive and boosts muscle mass, making it central to 2 of society's rising preoccupations: The anabolic effects of AAS have been questioned for decades, but recent scientific investigation of supraphysiologic doses supports the efficacy of these regimens.
Testosterone has potent anabolic effects on the musculoskeletal system, including an increase in lean body mass, a dose-related hypertrophy of muscle fibers, and an increase in muscle strength. For athletes requiring speed and strength and men desiring a cosmetic muscle makeover, illegal steroids are a powerful lure, despite the risk of subjective side effects. Recent clinical studies have discovered novel therapeutic uses for physiologic doses of AAS, without any significant adverse effects in the short term.
In the wake of important scientific advances during the past decade, the positive and negative effects of AAS warrant reevaluation. Guidelines for the clinical evaluation of AAS users will be presented for sports medicine practitioners.
If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click on download. Skip to main content. The American Journal of Sports Medicine. Current Concepts in Anabolic-Androgenic Steroids.
Evans , MD Nick A. Download PDF Article information. Keywords anabolic steroids , testosterone , androgen , anabolism , athletic performance , doping.
Vol 32, Issue 2, Vol 32, Issue 2, pp. Permissions Request Permissions View permissions information for this article. Send me a copy Cancel. Gluteal mass in a bodybuilder: Androgens in men—uses and abuses.
N Eng J Med. Psychological and behavioral effects of endogenous testosterone and anabolic-androgenic steroids. The anabolic action of testosterone. The effect of anabolic steroids and corticosteroids on healing of muscle contusion injury.
Am J Sports Med. Bhasin, S, Bremner, WJ. J Clin Endocrinol Metab. The effects of supraphysiological doses of testosterone on muscle size and strength in normal men.
A replacement dose of testosterone increases fat-free mass and muscle size in hypogonadal men. Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels. Testosterone doseresponse relationships in healthy young men. Am J Physiol Endocrinol Metab. Blazevich, AJ, Giorgi, A. Effect of testosterone administration and weight training on muscle architecture.
Med Sci Sports Exerc. Use of anabolic steroids and associated health risks among gay men attending London gyms. Reversible hypogonadism and azoospermia as a result anabolic-androgenic steroid use in a bodybuilder with personality disorder.
J Sports Med Phys Fitness. Single and combined effects of growth hormone and testosterone administration on measures of body composition, physical performance, mood, sexual function, bone turnover, and muscle gene expression in healthy older men.
Effects of testosterone replacement on muscle mass and muscle protein synthesis in hypogonadal men: Anabolic interventions for agingassociated sarcopenia. J Clin Endocrinol Metab ; Anabolic steroid abuse and dependence. Google Scholar , Crossref , Medline. Withdrawal from anabolic steroids.
Curr Ther Endocinol Metab. Google Scholar , Medline. Risk factors for anabolic-androgenic steroid use in men. Anabolic steroid abuse and renal cell carcinoma.
Estimated prevalence of anabolic steroid use among male high school seniors. Steroid receptor concentration in aged rat hind-limb muscle: Cerebrospinal fluid and behavioral changes after methyl testosterone administration: Is there a role for androgenic anabolic steroids in medical practice?
Anabolic steroids and the orthopaedic surgeon. J Bone Joint Surg Br. Br J Sports Med. Local complications of self-administered anabolic steroid injections. Ultrastructural analysis of ruptured tendon from anabolic steroid users. Stimulation of collagen synthesis by the anabolic steroid stanozolol. Testosterone injection stimulates net protein synthesis but not tissue amino acid transport. Intratesticular leiomyosarcoma in a young man after high dose doping with oral Turinabol: Anabolic steroid induced hypogonadism treated with human chorionic gonadotrophin.
Effect of testosterone on muscle mass and muscle protein synthesis. Effects of testosterone and progressive resistance training in eugonadal men with AIDS wasting: Anabolic steroids and growth hormone. Positive effects of anabolic steroids, vitamin D and calcium on muscle mass, bone mineral density and clinical function after hip fracture. Google Scholar , Crossref. Serum testosterone and sex hormone-binding globulin concentrations and the risk of prostate cancer. A thirty-year old bodybuilder with septic shock and ARDS from abuse of anabolic steroids.
The effect of anabolic steroids on rat tendon: Androgen receptor antagonist suppresses exercise-induced hypertrophy of skeletal muscle. Eur J Appl Physiol. Steroid use among adolescents: Anabolic steroid-induced hypogonadotrophic hypogonadism.
The expression of androgen receptors in human neck and limb muscles: Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism.
J Strength Cond Res. Recent Prog Horm Res. Are you man enough? Anabolic steroid induced tendon pathology: Anabolic Steroid Reference Manual. Molecular Nutrition ; Anabolic steroid abuse by body builders and male subfertility. Testosterone suppression of the HPT axis. Testosterone deficiency in young men: NCAA drug use and abuse study: Cardiovascular effects of androgenicanabolic steroids. The effect of anabolic steroids on the biomechanical and histological properties of rat tendon.
J Bone Joint Surg. Multiple hepatic adenomas caused by long term administration of anabolic steroids for aplastic anemia in association with familial adenomatous polyposis. National Institute on Drug Abuse. About anabolic steroid abuse. Selective androgen receptor modulators SARMs: The effect of supraphysiological doses of anabolic androgenic steroids on collagen metabolism. Int J Sports Med. Increased premature mortality of competitive power lifters suspected to have used anabolic agents.