What Is the Best Oral Steroid for Muscle Gain?I've never done steroids before, but I'm thinking of giving them a go. I'll probably be using orals since they're safer, plus I'm not exactly ready to proteina anabolic monster whey tubing around my arm and start poking around for a vein! Anyway, I was wondering how many anabolic steroids oral I should take. I know, I know, you probably have the urge to reach through your computer, drag Tom out on his undereducated butt, anabolic steroids oral beat some sense into him. Tom obviously doesn't know enough about steroids to even be thinking hgh boldenone kuur starting a cycle. He doesn't realize that steroids are designed for intramuscular use not intravenous usehe thinks orals are safer, and based on his question, I anabolic steroids oral think he even knows that there are different kinds of anabolic steroids oral
safe oral cycle for first timers?
The topic of oral steroids is perhaps the most popular topic among especially newcomers and prospective anabolic steroid users. There exists no greater attraction to those looking into using anabolic steroids for the first time than the attraction of the convenience of anabolic steroids in a very convenient easy to swallow pill or capsule format.
They are the following:. Oral steroids are safer than injectables. Oral steroids are easier to obtain. Oral steroids are cheaper. The real truth is that both injectable and oral steroids both contain various risky compounds in each category. There exist oral steroids that present a higher risk of various dangers to the body, while there are also injectable steroids that present higher risks as well.
This is not a problem present with the majority of injectables with the exception of a select one or two, as the majority of injectable compounds are well tolerated by the body. The specific details in regards to why this is the case will be explained shortly in this article. Oral steroids are not stronger than injectable steroids, nor are they weaker.
The anabolic strength rating the determined measurement of how effective an anabolic steroid is in terms of the promotion of muscle growth of various oral anabolic steroids does indeed match or surpass the anabolic strength rating of many injectable compounds, while several oral anabolic steroids fall short when compared to injectable compounds as well. Simply put, this is not true. There exists highly popular anabolic steroids in both categories that are very easy to obtain, but it just so happens to be that the most popular anabolic steroid of all time is an oral steroid Dianabol , AKA Methandrostenolone.
Aside from this, the next two most popular anabolic steroids of all time are both injectables: Nandrolone Deca Durabolin and Winstrol Stanozolol. All anabolic steroid sources and vendors should carry all types of oral steroids and injectable steroids in equal amounts available for purchase. This is also not true. Within both categories oral and injectable , there are both more expensive compounds as well as less expensive compounds, all related to factors such as popularity of the compound, ease of manufacture, ease of access, and so on and so forth.
The overall price of an anabolic steroid cycle will also normally end up being the same in general, as anabolic steroid cycles should ideally be pre-planned and all costs and dosages calculated prior to purchase.
At the end of the day, the overall cost of the amount of oral steroids to run in any given cycle is often almost the same price as any other injectable compound, with the exception of various more expensive compounds as mentioned prior. However, when compared to many injectable compounds, simple cycles, for example, of an injectable format of Testosterone ends up being far more cost effective than oral steroid cycles.
It is absolutely imperative to understand that the only three conventionally and commercially available oral steroids that are bioavailable orally without the need for chemical modification are Andriol, Primobolan , and Proviron.
Other than these three, all oral anabolic steroids must have previously undergone a specific modification in order to allow oral bioavailability. When Testosterone or any other anabolic steroid is ingested orally, very little of it will enter the bloodstream — too little, in fact, to impart any significant effects on the body.
This is because all ingested substances that are swallowed and processed through the gastrointestinal GI tract must always undergo what is known as a first pass through the liver prior to finally entering the bloodstream. Unfortunately, nearly all anabolic steroids are very easily metabolized and broken down by the liver, leaving a very miniscule percentage that actually survives this liver metabolism.
This chemical bonding of a methyl group onto the 17 th carbon is known as Calpha alkylation. As previously mentioned, when an anabolic steroid becomes Calpha alkylated, it allows an anabolic steroid to become orally active and bioavailable — without it, the anabolic steroid would not survive liver metabolism.
However, the negative downside in this case is that of increased hepatotoxicity increased liver toxicity. Calpha alkylation allows an anabolic steroid to become more resistant to hepatic breakdown, and any compound that is further resistant to hepatic breakdown will always have greater hepatotoxicity associated with it for various reasons. A methyl group, which is a central carbon atom bound to three hydrogen atoms, with one available opening to bond to the steroid molecule.
Indicated above is the difference between Testosterone without methylation Calpha alkylation and beside it is an image of Methyltestosterone, which is of course, Calpha alkylated Testosterone in order to allow Testosterone to become bioavailable orally and survive liver metabolism. The added methyl group is then indicated by the broken up red lines forming an arrow-like point at the 17 th carbon position, indicating that the methyl group is resting behind the visible orientation of the molecule shown a solid line forming an arrow-like point indicates the methyl group is situated in front of the visible orientation of the molecule.
The Calpha alkylation of an anabolic steroid therefore places select limitations on how it can be utilized, how long it can be used, and the dosing schemes of an oral steroid. These limitations surround its hepatotoxic effects on the liver, as well as its deleterious effects on cholesterol levels in the body. The following is a list of the most popular and most common Calpha alkylated oral steroids in order of popularity:. It is important to understand that not all Calpha alkylated oral steroids exhibit the same amount or level of hepatotoxicity.
There are various oral steroids that are known to be significantly hepatotoxic such as Anadrol, AKA Oxymetholone , while there are oral steroids that are known as being fairly mild in terms of their hepatotoxicity such as Anavar, AKA Oxandrolone.
A perfect example of this is the anabolic steroid Trenbolone, which is an injectable anabolic steroid that does not possess Calpha alkylation, and on its own does not exhibit any notable hepatotoxicity. It is, however, known to be quite resistant to hepatic metabolism on its own right. Following Calpha alkylation of it, creating Methyltrienolone, it then exhibits one of the most extreme degrees of liver toxicity ever reported — so much so that it is in fact for the most part un-useable.
All C alpha alkylated oral steroids have displayed at least some level of hepatotoxicity in studies, and what is very important to make note of is the fact that in many of these studies, doses utilized were medical therapeutic prescription doses that are generally doses of oral steroids that are far lower than those the doses of oral steroids required for performance and physique enhancement.
A perfect example to examine is Dianabol, as it is without a doubt the most popular oral anabolic steroid. Studies have demonstrated that Dianabol doses of 15mg per day or more displayed elevated bromosulphalein levels an indication of increased hepatic strain , and at doses of 10mg or less per day displayed minimal hepatic strain .
In terms of how the doses in the aforementioned study relate to real world bodybuilding doses, one could easily see how liver toxicity could potentially become an issue seeing as though the minimum beginner dose for bodybuilding purposes for something like Dianabol is no less than 25mg per day on average.
The most common form of hepatotoxicity as a result of excessive oral anabolic steroid use is known as a condition called Cholestasis . This is a condition whereby bile flow in the liver becomes either completely halted or at the very least disrupted. This can result from either a physical blockage, or a chemical one as is the case with anabolic steroid induced cholestasis of the liver.
What occurs here is that the blockage or chemical impairment results in a buildup of bile salts and bilirubin in the liver and bloodstream. In large enough quantities, this build-up can become toxic to the hepatic cells of the liver and kill them.
The severity of this condition can range from very minor and discomforting to life-threatening. Minor cases are recoverable in a matter of weeks while more severe cases may require months or more of recovery time. The excessive abuse of oral steroid doses as well as oral steroid cycle lengths can potentially cause very serious liver problems that can and have in the past become life-threatening.
Many individuals have developed liver cysts, hepatocellular necrotic lesions liver cell death and scarring of liver tissue , and in rare cases, hepatic angioscarcomas and hepatocellular carcinoma liver cancers. These have been found in a couple of bodybuilders following high-dose regimens of oral anabolic steroids  , as well as one well documented death .
It is a well-known and very well documented fact that anabolic steroids can and do exhibit negative cholesterol changes on the body, and various anabolic steroids exhibit this to a lesser extent, and some to a greater extent, while some anabolic steroids have displayed the ability to alter cholesterol levels in a positive manner though this is very rare. In the case of oral steroids, this negative impact on cholesterol levels is in fact the worst of all types of anabolic steroids.
The result of such changes involves an increased risk of arteriosclerosis, and the degree to which these changes occur for the worse are usually dose-dependent with higher doses increasing the negative changes and the risks. Other factors that affect these negative cholesterol changes are: This is where oral anabolic steroids hold a negative reputation for exhibiting a far worse negative impact on cholesterol in comparison to injectable anabolic steroids.
This is because the liver serves to function as the cholesterol processing center for the human body, and the increased hepatotoxicity associated with anabolic steroids will result in even worse negative cholesterol changes.
This results in less HDL cholesterol in circulation in the body during anabolic steroid use. First, injectable steroids and their impacts on cholesterol levels will be examined.
This data suggests that the impact of cholesterol alterations by injectable Testosterone is not extremely prominent, and that the ceiling for how much of a negative change in HDL will occur seems to be very low.
It is very evident that the negative impact on cholesterol by oral steroids is significant enough to warrant concern. As a result of the prominent issues of hepatotoxicity and negative cholesterol changes, it would then be a very smart decision and is in fact advised even among the medical establishment in prescription guidelines for the use of oral steroids to run oral steroids for periods no greater than 6 — 8 weeks at any given time in a cycle.
This is to ensure healthy liver function, and for proper liver recovery following the cycle. Various oral steroids that are known to exhibit more liver toxicity than others are advised to be used in the range of 4 — 6 weeks, while others can be utilized in the range of 6 — 8 weeks and some perhaps slightly longer 10 weeks maximum.
Due diligence must always be undertaken when using oral anabolic steroids in terms of proper liver function and liver health.
It is because of the risk of hepatotoxicity that the main function of oral steroids in any cycle is to primarily serve as a supplementary compound to a solid base of injectable compounds or as a supportive kickstarting compound. No oral steroid should ever be run solitarily on its own. Testosterone in some form no lower than a TRT Testosterone Replacement Therapy dose should always be run with an oral steroid.
It is imperative that all individuals especially beginners must understand the following very important guideline where anabolic steroid use is concerned:. Absolutely no cycle should ever consist of only oral anabolic steroids under any circumstances. The decision to run a cycle consisting of only a single anabolic steroid and no injectable compounds is most usually the very first decision of any beginner or prospective individual looking to begin anabolic steroid use.
This is usually the result of a fear of needles, but this must be overcome, and once overcome it becomes much easier afterwards. Oral anabolic steroids are not designed to be run solitarily on their own , and instead serve to act as supplementary compounds to a solid base cycle that should always include injectable compounds, of which an essentially required injectable being Testosterone for every single cycle.
Injectable compounds are the base compounds of any cycle. For individuals insistent and adamant on engaging in an oral-only cycle, a few examples will be provided very shortly, towards the end of this article. This is a technique whereby the user will include an oral anabolic steroid in a cycle for the first several weeks this is usually done in tandem with a long-estered injectable anabolic steroid due to the longer kick-in period.
Because the kick-in period for most injectables especially long esters is a matter of a few weeks into a cycle, one usually will not experience the positive effects until such time.
The oral anabolic steroid utilized during these first few weeks will enable the user to experience the positive anabolic effects of the oral while the effects of the injectable compound slowly increase. Dianabol is one such anabolic steroid that is commonly utilized to this effect as a kickstarting compound due to its considerable anabolic strength. Oral Steroid Cycle Example 1 Weeks 1 — Oral Steroid Cycle Example 2 Weeks Oral Steroid Cycle Example 3 high-dose short-term advanced level cycle of 4 weeks Weeks 1 — 4: As previously stated, the idea of running a cycle that consists of only oral steroids is, simply put, a bad idea.
Without any form of exogenous Testosterone, the body will be incapable of maintaining its normal physiological functions that are normally governed by Testosterone. Other anabolic steroid analogues and derivatives such as oral steroids might perhaps be several times as anabolic as Testosterone, but those are all the benefits most of these compounds possess.
For example, Dianabol is a very strong oral steroid with fairly low androgenic effects and very strong anabolic effects — however, it is not a proper androgen for normal bodily function.
The human body and endocrine system are not as simplified as many individuals make it out to be when trivializing an oral steroid only cycle. Testosterone is vital for proper libido function, it is a regulator of cognitive and physical energy, it regulates the population of thromboxane A2 receptors on megakaryocytes and platelets, and hence platelet aggregation in humans, and it is essential for proper mental and psychological function, and a plethora of other essential functions — so many in fact that a completely separate article could be composed on such a subject and discussed to no end.
Many anabolic steroids do nothing in many of those physiological functions that Testosterone is responsible for regulating and governing. Many other anabolic steroid analogues can also serve to in fact mitigate those functions. The importance of Testosterone notwithstanding, oral-only cycles are extremely limited in the manner by which they can be run.
They must be halted earlier than a normal cycle due to the issues of hepatotoxicity, and only one compound at any one given time can be run. The compounding of two or more oral anabolic steroids is a surefire way of dooming the liver to a highly toxic and very unhealthy environment.
No more than one oral steroid should be stacked at any one given time, even within properly structured anabolic steroid cycles.