Learn more about Goldenseal uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Goldenseal. The herb goldenseal has been said to cure a variety of illnesses, from pneumonia to bladder infections. Native Americans once used it to treat. As part of the buttercup family of plants, the goldenseal root is one of the more popular natural herbs that you can buy on the market today. The goldenseal root has many benefits for the body, especially when mixed with Echinacea. Goldenseal extract is also added to several skin.
Serious report these to your healthcare provider right away: Long term usage can lead to seizures, irregular heartbeat, trouble breathing, stomach problems, low blood pressure. Diarrhea; stomach upset; irritation to the throat, skin, mouth and vagina; nausea; vomiting; rash; nervousness; depression.
When you take this remedy with other medicines, it can change the way the remedy or the medicines work. Vitamins and certain foods may also interact. Using these products together might cause harmful side effects. Before taking this remedy, talk to your healthcare provider if you are taking:. If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you.
List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking. This advisory includes select information only.
The information was obtained from scientific journals, study reports, and other documents. The author and publisher make no warranty, expressed or implied, as to the information. The advisory may not include all side effects associated with a remedy or interactions with other medicines. Nothing herein shall constitute a recommendation for the use of any remedy.
Ask your healthcare provider or pharmacist for more information. GOLD-en-seel What are other names for this remedy? Hydrastis canadensis , goldenseal, ground raspberry, indian dye, jaundice root, orange root, yellow indian paint, hydrastis, goldenroot What is goldenseal?
What is it used for? Goldenseal has been taken by mouth to treat: Colds, flu, sinus infections, and hay fever Diarrhea Stomach upset Hemorrhoids Menstrual problems It may be used with echinacea to treat colds and the flu.
How is it taken? Do not take goldenseal for longer than 2 weeks. Do not take higher dosages than recommended. What if I overdose?
Symptoms of an acute overdose have not been reported. What should I watch out for? Talk with your healthcare provider before taking this remedy if you have: Heart disease Colitis or other inflammation of the intestines High blood pressure Seizures Goldenseal can be poisonous if you use too much. Do not use goldenseal on newborns. It may increase jaundice and cause brain damage. Natural remedies are not always safe. You should not take them if you are pregnant or breast-feeding without your healthcare provider's approval.
They should not be taken by infants, children, or older adults without your provider's approval. Fair scientific evidence for this use it may not work F: They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven.
There may be other proposed uses that are not listed below. Dosing Adults 18 years and older Historically, goldenseal has been used in various formulations. The following doses have been used, each taken three times daily: To treat heart failure, 1. To treat high cholesterol, 0. To treat infectious diarrhea, milligrams of berberine hydrochloride four times daily or a single dose of milligrams has been taken by mouth. A dose of 50 milligrams of berberine hydrochloride has been taken every eight hours for two days, followed by 50 milligrams twice daily until the fifth day.
Berberine sulfate is often used as well, and the hydrochloride and sulfate forms are generally considered interchangeable. To treat stimulation of the immune system in people with low white blood cell count, 50 milligrams of berberine has been taken by mouth three times daily for weeks.
To treat trachoma Chlamydia trachomatis eye infection , two drops of 0. Children younger than 18 years To treat diarrhea, milligrams of berberine has been taken by mouth four times daily.
To treat trachoma Chlamydia trachomatis eye infection , a treatment consisting of 0. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary.
You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects. Allergies Avoid in people with a known allergy or sensitivity to goldenseal Hydrastis canadensis , any of its parts, including berberine and hydrastine, or to members of the Ranunculaceae family.
Side Effects and Warnings Berberine is likely safe when used short-term in recommended doses. Berberine may lower blood sugar levels. Caution is advised in people with diabetes or hypoglycemia, and in those taking drugs, herbs, or supplements that affect blood sugar. Blood glucose levels may need to be monitored by a qualified healthcare professional, including a pharmacist, and medication adjustments may be necessary.
Goldenseal or berberine may increase the risk of bleeding. Caution is advised in people with bleeding disorders or taking drugs that may increase the risk of bleeding. Dosing adjustments may be necessary. Goldenseal or berberine may cause low blood pressure. Caution is advised in people taking drugs or herbs and supplements that lower blood pressure.
Drowsiness or sedation may occur. Use caution if driving or operating heavy machinery. Use cautiously in people with heart disease or gastrointestinal disorders. Use cautiously in people taking agents that may alter immune function, agents that may increase sensitivity to the sun, and agents processed by the liver. Avoid in pregnant women and children. Avoid in infants with increased bilirubin levels or people with glucosephosphate deficiency.
Avoid in people with a known allergy or sensitivity to goldenseal Hydrastis canadensis , any of its parts, including berberine and hydrastine, or to members of the Ranunculaceae family.
Adding other alkaloid-containing herbs to goldenseal, including Chinese goldthread Coptis chinensis and Oregon grape, may increase the risk of adverse events. Goldenseal may also cause benign or malignant liver tumors, brain damage from bilirubin, exacerbation of peptic ulcer disease, increased sensitivity to the sun, low heart rate, mucous membrane dryness, irritation, or ulcers, narrowed blood vessels, nausea, numbness, respiratory failure, reversible increase in blood sodium levels, vomiting, or yellowing of the skin.
Berberine may also cause antidiarrheal effects, faster or slower heart rate, headache, increase or decrease in white blood cell count, increase bilirubin concentration, nausea, stomach discomfort or bloating, or vomiting. Pregnancy and Breastfeeding Goldenseal or its active component hydrastine taken by mouth may induce labor and should not be used by pregnant women. Berberine-containing herbs such as goldenseal have been suggested historically to induce abortion. Goldenseal preparations with Chinese goldthread Coptis chinensis were reportedly associated with multiple cases of brain damage from bilirubin in Asia in the s and s.
Goldenseal, at the prescribed human dose, is unlikely to be unsafe during pregnancy in humans, despite the apparent toxic effects in animal studies. However, additional studies are needed before a firm conclusion may be made.
Goldenseal has been used for sore nipples. A component of goldenseal, berberine, may cause brain damage in infants and may theoretically be present in breast milk due to its interaction with albumin. Goldenseal is not recommended during breastfeeding, due to a lack of sufficient data.
Interactions Interactions with Drugs Berberine may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. People taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary. Goldenseal or its component berberine may increase the risk of bleeding when taken with drugs that increase the risk of bleeding. Goldenseal may interfere with the way the body processes certain drugs using the liver's "cytochrome P" enzyme system.
As a result, the levels of these drugs may be decreased in the blood, and reduce the intended effects. People taking any medications should check the package insert and speak with a qualified healthcare professional, including a pharmacist, about possible interactions. Goldenseal may affect blood pressure. Caution is advised in people taking agents that lower blood pressure. Goldenseal may increase the amount of drowsiness caused by some drugs.
Caution is advised while driving or operating machinery. Interactions with Herbs and Dietary Supplements Berberine may lower blood sugar levels. Caution is advised when using herbs or supplements that may also lower blood sugar.
Blood glucose levels may require monitoring, and doses may need adjustment. Goldenseal or its component berberine may increase the risk of bleeding when taken with herbs and supplements that are believed to increase the risk of bleeding. Multiple cases of bleeding have been reported with the use of Ginkgo biloba , and fewer cases with garlic and saw palmetto. Numerous other agents may theoretically increase the risk of bleeding, although this has not been proven in most cases.
Goldenseal or its component berberine may interfere with the way the body processes certain herbs or supplements using the liver's "cytochrome P" enzyme system. As a result, the levels of other herbs or supplements may become too high in the blood. It may also alter the effects that other herbs or supplements possibly have on the P system.
Goldenseal may increase the amount of drowsiness caused by some herbs or supplements. Goldenseal or its component berberine may also interact with alkaloids; antibacterials; antihistamines; anti-inflammatory herbs and supplements; berberine-containing herbs and supplements; cholesterol lowering herbs and supplements; foxglove; herbs and supplements against fungi or helminths; herbs and supplements for abnormal heart rhythm; herbs and supplements for cancer, diarrhea, or malaria; herbs and supplements for the brain, heart, intestines and stomach; herbs and supplements that alter heart rate; herbs and supplements that may alter immune function; herbs and supplements that may increase sensitivity to the sun; herbs or supplements that may narrow blood vessels; herbs and supplements toxic to the liver; laxatives; marijuana; wound-healing herbs and supplements; yohimbe.
Attribution This information is based on a systematic review of scientific literature edited and peer-reviewed by contributors to the Natural Standard Research Collaboration www. Severe hypernatremia and hyperosmolality exacerbated by an herbal preparation in a patient with diabetic ketoacidosis.
Clin Pediatr Phila Nov;46 9: Berberine--a novel approach to cholesterol lowering. Supplementation with goldenseal Hydrastis canadensis , but not kava kava Piper methysticum , inhibits human CYP3A activity in vivo. Clin Pharmacol Ther Jan;83 1: Pharmacokinetic herb-drug interactions part 2:
5 Facts About Goldenseal Extract
Goldenseal suggested uses include for the common cold, conjunctivitis, diarrhea, dysmenorrhea/menorrhagia, flatulence, gastritis/colitis. Can goldenseal help treat infections? Find out here. Native Americans have been using goldenseal for a long time, and have revered it for its wide array of health benefits. This valuable herb is.