Pure and Organic CBD & and Hemp Products

Effective medicine provided by mother nature

  • Powerful relaxant

  • Strong painkiller

  • Stress reduction
  • Energy booster

Why CBD?

More and more renowned scientists worldwide publish their researches on the favorable impact of CBD on the human body. Not only does this natural compound deal with physical symptoms, but also it helps with emotional disorders. Distinctly positive results with no side effects make CBD products nothing but a phenomenal success.

This organic product helps cope with:

  • Tight muscles
  • Joint pain
  • Stress and anxiety
  • Depression
  • Sleep disorder

Range of Products

We have created a range of products so you can pick the most convenient ones depending on your needs and likes.

CBD Capsules Morning/Day/Night:

CBD Capsules

These capsules increase the energy level as you fight stress and sleep disorder. Only 1-2 capsules every day with your supplements will help you address fatigue and anxiety and improve your overall state of health.

Order Now

CBD Tincture

CBD Tincture

No more muscle tension, joints inflammation and backache with this easy-to-use dropper. Combined with coconut oil, CBD Tincture purifies the body and relieves pain. And the bottle is of such a convenient size that you can always take it with you.

Order Now

Pure CBD Freeze

Pure CBD Freeze

Even the most excruciating pain can be dealt with the help of this effective natural CBD-freeze. Once applied on the skin, this product will localize the pain without ever getting into the bloodstream.

Order Now

Pure CBD Lotion

Pure CBD Lotion

This lotion offers you multiple advantages. First, it moisturizes the skin to make elastic. And second, it takes care of the inflammation and pain. Coconut oil and Shia butter is extremely beneficial for the health and beauty of your skin.

Order Now

WHY DO PEOPLE CHOOSE CBD GUMMIES OVER OTHER FORMS OF CBD?

» Phytocannabinoid

vfvfvfhbyf
20.07.2018

Content:

  • » Phytocannabinoid
  • Intro to Phytocannabinoids
  • INTRODUCTION
  • Phytocannabinoids are cannabinoids that occur naturally in the cannabis plant. These cannabinoids are abundant in the viscous resin that is produced by glandular structures in the cannabis plant called trichomes. Other common cannabinoids include cannabidiol (CBD) and cannabinol. Surg Neurol Int. Apr 26; doi: /rodance.info_45_ eCollection Review of the neurological benefits of phytocannabinoids. Maroon J(1), Bost. It is intriguing that during human cultural evolution man has detected plant natural products that appear to target key protein receptors of important physiological.

    » Phytocannabinoid

    Phytocannabinoids are a key chemical component in the cannabis plant. The cannabis plant contains compounds that have been identified by researchers, out of those compounds are considered phytocannabinoids. Different strains of cannabis contain varying levels of the different phytocannabinoids. Growers frequently cultivate marijuana plants to contain higher or lower levels of such cannabinoids, especially THC and CBD. Phytocannabinoids are, for the most part, insoluble in water but are soluble in alcohols, fats, and other non-polar organic solvents.

    Definition - What does Phytocannabinoids mean? MaximumYield explains Phytocannabinoids Because of the cannabis plant's unique phytocannabinoids, the use of medicinal marijuana has become commonplace in many areas of the world as an acceptable treatment for numerous diseases and disorders.

    Breeding with Autoflowering Cannabis. Multiple sclerosis CBD and deltaTHC MS is an autoimmune disease that promotes demyelination of neurons and subsequent aberrant neuronal firing that contributes to spasticity and neuropathic pain. Use of cannabis-based medicine for neurodegenerative conditions The use of cannabis-based medicine for the treatment of MS has a long history and its interaction with the ECS shares many of the same pathways of other neurodegenerative conditions.

    American Academy of Neurology statement on medical marijuana In , the American Academy of Neurology AAN published a review article of 34 studies investigating the use of medical marijuana as extracts, whole plants and synthetic phytocannabinoids for possible neurological clinical benefits.

    MS animal models utilizing deltaTHC MS animal models using autoimmune encephalomyelitis EAE have been used that demonstrate demyelination, neuroinflammation, and neurological dysfunction associated with infiltration of immune cells into the CNS consistent with the human disease.

    Neuropsychiatric and brain trauma Cannabidiol CBD is recognized as a nonpsychoactive phytocannabinoid. Antidepressant and neuroprotective properties Antidepressants, used for the treatment of depression and some anxiety disorders, also possess numerous neuroprotective properties, such as preventing the formation of amyloid plaques, elevation of BDNF levels, reduction of microglia activation, and decreased levels of proinflammatory mediators.

    Rat models; efficacy of CBD in neurobehavioral disorders In rat models of neurobehavioral disorders, CBD demonstrated attenuation of acute autonomic responses evoked by stress, inducing anxiolytic and antidepressive effects by activating 5HT1A receptors in a similar manner as the pharmaceutical buspirone that is approved for relieving anxiety and depression in humans.

    Human imaging studies correlated with CBD Human imaging studies have demonstrated CBD affects brain areas involved in the neurobiology of psychiatric disorders. Tetrahydrocannabinol Interestingly, THC, administered prior to a traumatic insult in human case studies and animal models has had measurable neuroprotective effects.

    Utility for glioblastoma multiforme Glioblastoma multiforme GBM is the most frequent class of malignant primary brain tumors. CBD reduces growth different tumor xenografts CBD has also been shown to reduce the growth of different types of tumor xenografts including gliomas. Intractable epilepsy Cannabidiol Reports of cannabis use in the treatment of epilepsy appear as far back as BC. CBDs reduce neuronal hyperactivity in epilepsy CBD's overall effect appears to result in reduction of neuronal hyperactivity in epilepsy.

    Endogenous cannabinoids Endogenous cannabinoids appear to affect the initiation, propagation, and spread of seizures. Safety A comprehensive safety and side effect review of CBD in on both animal and human studies described an excellent safety profile of CBD in humans at a wide variety of doses.

    CBD — better safety profile vs. Adverse effects The AAN review of 34 articles on MS using cannabinoids of various forms noted several adverse effects. Prescribing medical marijuana Ultimately, prescribing medical marijuana either as a primary treatment or adjunctive therapy will require extreme care and knowledge about the patient's goals and expectations for treatment.

    Have you counseled the patient documented by the patient's signed informed consent regarding the medical risks of the use of marijuana—medical, psychological, and social such as impairment of driving or work skills and habituation? Does your patient have a history of misused marijuana or other psychoactive, addictive prescription and illegal drugs? Will you know the standardization and potency content of the medical marijuana to be used and whether it is free of contaminants?

    Legalization of marijuana in many states: Need for education Because of the rapid legalization of medical marijuana by the majority of state legislatures in the U.

    Financial support and sponsorship Nil. Conflicts of interest The Authors report the following conflicts: Abush H, Akirav I. Cannabinoids control spasticity and tremor in a multiple sclerosis model. Safety and side effects of cannabidiol: A Cannabis sativa constituent.

    Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naive social phobia patients. Molecular targets of cannabidiol in neurological disorders.

    The bad side of adenosine. Translating depression biomarkers for improved targeted therapies. Plastic and neuroprotective mechanisms involved in the therapeutic effects of cannabidiol in psychiatric disorders.

    Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. Cannabidiol, neuroprotection and neuropsychiatric disorders.

    Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes. The stress-regulated protein p8 mediates cannabinoid-induced ptosis of tumor cells. Cassan C, Liblau RS. Immune tolerance and control of CNS autoimmunity: From animal models to MS patients.

    The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic—ischemic brain damage in mice is mediated by CB2 and adenosine receptors. Neuronal network plasticity and recovery from depression. The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis. Effects of cannabidiol on behavioral seizures caused by convulsant drugs or current in mice. Controlled clinical trial of cannabidiol in Huntington's disease.

    The perceived effects of smoked cannabis on patients with multiple sclerosis. Open label evaluation of cannabidiol in dystonic movement disorders. Effects of cannabidiol CBD on regional cerebral blood flow. Chronic administration of cannabidiol to healthy volunteers and epileptic patients. Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: Pro-apoptotic effects and underlying mechanisms.

    Endocannabinoids block status epilepticus in cultured hippocampal neurons. Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders. Cannabidiol in patients with treatment-resistant epilepsy: An open-label interventional trial.

    Trial of cannabidiol for drug-resistant seizures in the Dravet syndrome. N Engl J Med. CB1 receptor selective activation inhibits beta-amyloid-induced iNOS protein expression in C6 cells and subsequently blunts tau protein hyperphosphorylation in co-cultured neurons. Cannabidiol reduces ab-induced neuroinflammation and promotes hippocampal neurogenesis through PPARc involvement. Prospects for cannabinoid therapies in basal ganglia disorders. The effect of cannabis on urge incontinence in patients with multiple sclerosis: Role of endogenous cannabinoids in synaptic signaling.

    Friedman D, Devinsky O. Cannabinoids in the treatment of epilepsy. Gaoni Y, Mechoulam R. Isolation structure and partial synthesis of an active constituent of hashish. J Am Chem Soc. Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: Importance of antioxidant and cannabinoid receptor-independent properties. Cannabinoid receptors in the human brain: Gloss D, Vickrey B. Cochrane Database Syst Rev. The multiplicity of action of cannabinoids: Implications for treating neurodegeneration.

    Grinspoon L, Bakalar JB. The use of cannabis as a mood stabilizer in bipolar disorder: Anecdotal evidence and the need for clinical research. Guo J, Ikeda SR. Endocannabinoids modulate N-type calcium channels and G-protein-coupled inwardly rectifying potassium channels via CB1 cannabinoid receptors heterologously expressed in mammalian neurons. A unified critical inventory. Hermann D, Schneider M. Potential protective effects of cannabidiol on neuroanatomical alterations in cannabis users and psychosis: Phytocannabinoids as novel therapeutic agents in CNS disorders.

    Medical marijuana for treatment of chronic pain and other medical and psychiatric problems: Endocannabinoids and vascular function. J Pharmacol Exp Ther. International Union of Pharmacology. Classification of cannabinoid receptors. A review of the evidence for efficacy of complementary and alternative medicines in MS. Potential for the treatment of neuronal hyperexcitability. Iffland K, Grotenhermen F. Safety and Side Effects of Cannabidiol— A review of clinical data and relevant animal studies.

    Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain. Curr Med Res Opin. A promising drug for neurodegenerative disorders?

    Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures. Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo. A typical responsiveness of the orphan receptor GPR55 to cannabinoid ligands. Prolonged CNS hyperexcitability in mice after a single exposure to deltatetrahydrocannabinol.

    Kim D, Thayer SA. Efficacy and safety of medical marijuana in selected neurologic disorders, Report of the Guideline Development Subcommittee of the American Academy of Neurology. Dopamine modulation of state-dependent endocannabinoid release and long-term depression in the striatum. Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia.

    From phytocannabinoids to cannabinoid receptors and endocannabinoids: Pleiotropic physiological and pathological roles through complex pharmacology. Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma.

    An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis. Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli.

    The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells. Cell Mol Life Sci. Cannabidiol induces intracellular calcium elevation and cytotoxicity in oligodendrocytes.

    Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. Breast Cancer Res Treat. Handbook of Cannabis and Related Pathologies. Shinjyo N, Di Marzo V. Neurochem Int ;63 5: Inhibitory effect of cannabichromene, a major non?

    Br J Pharmacol ; 4: Papp J, et al. Differential effectiveness of selected non? Exp Dermatol ;25 9: De Meijer E, Hammond K. The inheritance of chemical phenotype in Cannabis sativa L. Beta-caryophyllene is a dietary cannabinoid. Proc Natl Acad Sci ; The cannabinoid CB2 receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain. Eur Neuropsychopharmacol ;24 4: J Biol Chem ; Alkylamides from Echinacea are a new class of cannabinomimetics Cannabinoid type 2 receptor-dependent and-independent immunomodulatory effects.

    Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin. Biochem Pharmacol ;79 Kavalactones Yangonin and Methysticin induce apoptosis in human hepatocytes HepG2 in vitro. Phytother Res ;25 3:

    Intro to Phytocannabinoids

    A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid . Phytocannabinoids are known to occur in several plant species besides cannabis. These include Echinacea purpurea, Echinacea angustifolia. Phytocannabinoids are the naturally occurring cannabinoids found in the cannabis plant. This is opposed to synthetic cannabinoids that are manufactured . It might interest you to know that there's actually a minimal difference between phytocannabinoids and cannabinoids.

    INTRODUCTION



    Comments

    savito1

    A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid . Phytocannabinoids are known to occur in several plant species besides cannabis. These include Echinacea purpurea, Echinacea angustifolia.

    xaxanoulhs

    Phytocannabinoids are the naturally occurring cannabinoids found in the cannabis plant. This is opposed to synthetic cannabinoids that are manufactured .

    futball

    It might interest you to know that there's actually a minimal difference between phytocannabinoids and cannabinoids.

    adasbafvjl

    Phytocannabinoid-rich oil is currently being researched so we can better understand the potential uses. However, people are already using.

    vono86

    Phytocannabinoid Oil: An Inside Look. Where phytocannabinoids come from and what makes phytocannabinoid products different. Cannabis is.

    Add Comment