Learn about the potential interactions between cannabinoids found in cannabis and other drugs, from blood sugar medications, to opioids, to alcohol. Unfortunately, few data are available regarding the potential drug interactions associated with marijuana. Nevertheless, we can make some. Some medications are changed and broken down by the liver. Marijuana might.
Does Drugs? With Cannabis | Interact Leafly How Other
Activating both receptors induces a cardiovascular stress response that can elevate cardiac oxygen consumption while reducing blood flow in coronary arteries. While reports of adverse events are relatively rare, patients who are taking blood pressure medication should be aware that cannabis may compound effects. By possibly slowing down the metabolism of these drugs. To a lesser extent, THC may displace warfarin from protein binding sites.
However, characterizing the specific mechanisms by which they interact proves challenging. Nonetheless, the pain-relieving properties of cannabis are well-established. And, many medical professionals have come forward to suggest cannabis as an alternative pain medication could play a role in stemming the overuse of prescription and illicit opioids.
However, what about as an adjunct to opioid therapy? How does cannabis measure up? Examining the subjective effects of vaporized cannabis in conjunction with opioids, Dr. Abrams concluded that cannabis can, in fact, safely augment the pain-relieving effects of opioids.
His team also found that combining opioids and cannabis may allow for treating patients with lower opioid doses while reducing risk of dependency and fewer side effects. Mixing alcohol with virtually any drug is generally not a good idea. In fact, mixing it with some drugs particularly opioids and central nervous system depressants like benzodiazepines, barbiturates, and sleep meds can prove fatal.
But, what about alcohol and cannabis? But what does the research say? Is mixing these two substances okay? Overall, drawing a conclusion based on available research is subject to interpretation and personal biases. The same studies can be interpreted positively or negatively, depending on your perspective. On the one hand, studies have provided compelling evidence that alcohol increases blood THC levels although no evidence suggests the converse—that THC increases blood alcohol levels.
On the other hand, some research suggests people consume less alcohol when they use cannabis. In fact, they make sense. If THC reacts to alcohol by potentiating the desired effects on mood, then one would need less alcohol. Concordance of Use by Men and Women , that examined consumption pattern differences in three different environments only alcohol is available, only cannabis is available, both are available. Basically, when people have access to both substances, their consumption patterns change: That being said, one still needs to be cautious.
For one, alcohol and cannabis together pose even greater dangers driving than when using either one independently. Second, if someone has had too much to drink—to the point they need to vomit to expel the toxins—know that cannabis inhibits nausea and vomiting.
Many sedatives—such as alcohol, benzodiazepines Ativan, Valium, etc. Although, each of these compounds produce effects differently, and sometimes paradoxically.
For example, higher doses of THC can actually be stimulating and increase anxiety, while CBD can be both calming or wake-inducing. When combined with sedatives, cannabis produces an additive effect. Users should exercise extreme caution, or better yet, avoid the combination altogether.
Although evidence suggests CBD is largely safe, well-tolerated, and non-addictive even anti-addictive , in some patients it can interact synergistically beneficially or adversely with other medications.
Most notably, the interplay between CBD and cytochrome P seems be most prominent when it comes to epilepsy and anti-seizure medications. One small study published in found that CBD elevated blood concentrations of clobazam an anticonvulsant in children while elevating norclobazam an active metabolite of clobazam. The good news is the remedy seems fairly straightforward: But in short, CBD inhibits breakdown of warfarin a blood thinner , thereby increasing its duration of action and effect.
Patients taking CBD-rich products should pay close attention to changes in blood levels and adjust dosage accordingly as instructed by their doctor. Also, patients who are undergoing chemotherapy and taking CBD should be aware that the same dose of chemotherapy may produce higher blood concentrations. For most patients, cannabis is relatively safe, well-tolerated, and carries fewer risks of adverse drug interactions than many other commonly prescribed drugs.
Influenced by these cannabinoid and terpene profiles, potential interactions, both good and bad, can vary from strain to strain. Nonetheless, given its therapeutic versatility, one of the most compelling arguments for cannabis is that it can actually reduce the need to combine multiple medications that have a high risk potential of producing adverse interactions. The bad news is that Cannabis can potentially magnify the side effects of certain prescriptions or substances.
As with any medication, you should always talk to your doctor before you change your dose or stop taking your medicine. Making changes to any medical regimen can be extremely dangerous without careful guidance from a qualified physician. Medical marijuana has helped countless patients manage their symptoms and enjoy a greater degree of physical comfort in their everyday lives. Call Inhale MD at to start discussing your medical needs in a confidential consultation.
Your email address will not be published. Harmful Drug Interactions to Avoid Many prescription drugs have harmful interactions with each other, with alcohol, or even with certain foods. In fact, as natural and synthetic drugs go, Cannabis is exceptionally gentle, with negative effects typically limited to: Anxiety Dry Mouth Increased Thirst Sore Throat All of these effects are temporary, and for most patients, fall well within the range of tolerability.
Here are some examples of how this can occur: That means you might become far more intoxicated than you bargained for, which can make it very dangerous to drive or operate heavy machinery.
Marijuana is sometimes described as a depressant. Some functions, however, such as heart rate, increase. When a patient combines marijuana with other medications that can also produce sedative effects, the resulting synergy can greatly magnify sensations of drowsiness or difficulty concentrating and making decisions.
Some examples of drugs this can occur with include: Cannabis can lower your blood pressure, particularly when you stand up from sitting or lying. This can lead to lightheadedness and even falling. You may need to increase or decrease your current dose if your blood pressure is significantly affected by Cannabis use.
Drugs that May Interact with CBD Oil
But that's not to say marijuana couldn't interact harmfully with other drugs CBD can slow down metabolization of cholesterol medications like. Before you take other drugs alongside cannabis, you should make sure there are no harmful interactions. Call a medical marijuana doctor for. They can be legally prescribed for the treatment of nausea and vomiting Interactions. Possible interactions include: Alcohol. Marijuana use.