Pure and Organic CBD & and Hemp Products

Effective medicine provided by mother nature

  • Powerful relaxant

  • Strong painkiller

  • Stress reduction
  • Energy booster

Why CBD?

More and more renowned scientists worldwide publish their researches on the favorable impact of CBD on the human body. Not only does this natural compound deal with physical symptoms, but also it helps with emotional disorders. Distinctly positive results with no side effects make CBD products nothing but a phenomenal success.

This organic product helps cope with:

  • Tight muscles
  • Joint pain
  • Stress and anxiety
  • Depression
  • Sleep disorder

Range of Products

We have created a range of products so you can pick the most convenient ones depending on your needs and likes.

CBD Capsules Morning/Day/Night:

CBD Capsules

These capsules increase the energy level as you fight stress and sleep disorder. Only 1-2 capsules every day with your supplements will help you address fatigue and anxiety and improve your overall state of health.

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CBD Tincture

CBD Tincture

No more muscle tension, joints inflammation and backache with this easy-to-use dropper. Combined with coconut oil, CBD Tincture purifies the body and relieves pain. And the bottle is of such a convenient size that you can always take it with you.

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Pure CBD Freeze

Pure CBD Freeze

Even the most excruciating pain can be dealt with the help of this effective natural CBD-freeze. Once applied on the skin, this product will localize the pain without ever getting into the bloodstream.

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Pure CBD Lotion

Pure CBD Lotion

This lotion offers you multiple advantages. First, it moisturizes the skin to make elastic. And second, it takes care of the inflammation and pain. Coconut oil and Shia butter is extremely beneficial for the health and beauty of your skin.

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Products Sleep Aid

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01.07.2018

Content:

  • Products Sleep Aid
  • Natural Sleep Aids & Tips
  • Read more tips, recipes, and insights on a wide variety of topics from Dr. Weil here.
  • From light-blocking eye masks to science-backed essential oils, these products may be the trick to dozing off for a good night's sleep. Our editors asked Insomnias and self-proclaimed "bad sleepers" for their favorite sleep aids, essential oils, and tech devices that help them get. Read reviews and buy the best sleep aid from top brands including test, and recommend the best products; you can learn more about our.

    Products Sleep Aid

    Insomnia is a relatively common sleep disorder, affecting about one-third of the adult population worldwide. Insomnia can cause severe sleeplessness and is more common in women, but the quality of sleep decreases equally in both women and men as we age. Typical symptoms of insomnia include problems falling asleep, waking up frequently in the night with difficulty falling back to sleep, waking too early in the morning, and feeling unrefreshed when waking in the morning.

    The causes of insomnia are varied. Noise, temperature changes, medication side effects, jet lag, and a change in surroundings can all cause insomnia, as can PMS, menopause, menstruation, or pregnancy.

    If you suffer from insomnia, try to stick to a routine at bedtime, and go to bed at the same time every day.

    Avoid caffeine and nicotine before bedtime, and get plenty of exercise during the day. If you are having trouble falling asleep, try relaxation techniques like breathing exercises, meditation, or yoga.

    Mantram is the practice of repeating over and over in the mind certain syllables, words or phrases that help unify consciousness and counteract negative mental states. It is especially helpful for people with restless minds, whose turbulent thoughts keep them from relaxing, concentrating and falling asleep. The repetition of a verbal formula is a way of focusing the thinking mind and counteracting the damage done to both mind and body by thoughts that produce anxiety , agitation and unhappiness.

    Try experimenting with it — choose a word, sound or phrase that is pleasing to you, and repeat it. If your mind wanders, simply focus back on the word. You will be amazed at the results. Stay Connected With Dr. Read more tips, recipes, and insights on a wide variety of topics from Dr.

    Sleep Issues Natural Insomnia Treatment. Weil's Guide To Essential Oils. Healthy Living Essential Oils: Sleep Issues Alarm Clocks: Alarmed in the A. Anti-Inflammatory Diet Follow Dr. Alternative approaches to treating insomnia have included an off-label basis for insomnia, over-the-counter sleep aids, and assorted unregulated substances marketed to enhance sleep. Substances regarded as appropriate hypnotics are those which prevent continuous awakenings, shorten the period of latency for sleep initiation and increase sleep duration, besides displaying low toxicity.

    Key physiological measurements indicators of sleep include electroencephalography EEG of brain waves, electrooculography EOG of eye movements, electromyography EMG of skeletal muscle activity. Simultaneous collection of these measurements is called polysomnography, and can be performed in a specialized sleep laboratory Rundell and Jones, Sleep researchers also use simplified electrocardiography ECG for cardiac activity and actigraphy for motor movements Jafari and Mohsenin, This has promoted the search for alternative approaches such as the employment of phythotherapeutic agents.

    Animal behavioral experiments were done after surgery and agent treatment Fig. EEG measurement experiment in the rats. To measure EEG changes, the rats were sutured after implantation of the transmitter body on the back of male rats. The electrode is inserted and fixed with dental cement after puncturing the skull.

    After one week of recovery from surgery, EEG is recorded. The sleep architecture is analyzed based on the EEG record, which is received on the computer. A number of medicinal plants are traditionally endowed with anxiolytic or sedative properties. This has motivated the searching of phythotherapeutic agents, which has been used in animal behavioral experiments performed by surgery Fig.

    In this context, there is a lot of information in medicinal plants possessing sedative and hypnotic properties. Here, we describe some natural products studied in our laboratory. These are magnolia Magnolia officinalis , Magnoliaceae , Semen zizyphi spinosae Zizyphus jujube Mill. Chemical structures originated from natural products which have been to be effective for sleep from our laboratory. Biophenolic compounds such as magnolol, honokiol, and obovatol isolated from M.

    In addition, research has shown that magnolol and honokiol are the primary active components of M. In addition, they have shown to increase the density of GABA A receptors that possess alpha subunits and this has been a mechanism followed by diazepam, a benzodiazepine sometimes used to treat insomnia, Ma et al.

    All together, these effects increase GABA activity, which promotes relaxation and reduces anxiety. Particularly, magnolia bark has been used for human treatment as an anxiolytic, helping to lower anxiety, depression, reduce stress, and facilitating sleep. These effects could be indicators of its positive potential as a natural sleep aiding agent. Semen zizyphi spinosae Rhamnaceae, the dried seed of Zizyphus jujube Mill var. It was reported that sanjoinine, which is a major alkaloid compound, and cyclopeptides from Semen zizyphi spinosae have have shown anxiolytic-like effects in the elevated plus-maze, hole-board test and open field test, and these effects may be mediated by GABA A -ergic transmission Han et al.

    However, it has been suggested for high affinity for 5-HT 1 a and 5-HT 2 receptors in in vivo analysis Yi et al. Sinomenine, an alkaloid derived from Sinomenium acutum , is a chief ingredient that has been reported to have a variety of pharmacological properties including anxiolytic effects Rao et al.

    From a recent experiment, sinomenine enhanced pentobarbital-induced sleeping behaviors, and modulate sleep architecture via GABA A -ergic systems in rodents, ultimately increasing NREM sleep. Decursinol is one of the major components of Angelica gigas Umbelliferea which has been used for a long time as a traditional folk medicine in oriental countries.

    This herb has been used traditionally for the treatment of psychosomatic disease such as excess stress, anxiety, depression and insomnia. It has been reported that the essential oil components of Angelica gigas exhibited anxiolytic-like effects in rodent tests Chen et al. Similarly, Japanese Angelica root extract reversed stress-induced loss of sleep in pentobarbital-induced sleeping in mice through the inhibition of the central noradrenergic or the activation of GABA A receptors Matsumoto et al.

    On the other hand, decurcinol potentiates pentobarbital-induced sleeping behaviors through the activation of GABA A -ergic systems. Altogether suggest that decurcinol, can be useful agent for the treatment of insomnia Woo et al.

    Rosemary fromPerilla frutescens, Lamiaceae has been used as a folk remedy for sedation in oriental countries. So far, several studies have shown that Perilla frutescens has sedative effect Takeda et al. Many of the phenolic compounds originating from plants have been known to affect the GABA-ergic systems Johnston et al. Rosmarinic acid augmented pentobarbital-induced sleeping behaviors through GABA A -ergic transmission.

    It is suggested that rosmarinic acid may be useful agent for the treatment of insomnia Kwon et al. Euphoria longan or Dimocarpus longan , Spindaceae is commonly consumed as the dried fruit of Euphoria longana. Phytochemicals such as gallic acid, ellastic acid and corilagin ellagitanin were identified from the peel, seed and pulp of its fruit Rang-Kadilok. The pulp of the dried fruit and fresh Longanae Arillus, has been used for the treatment of anxiety and insomnia in Asian countries.

    The extract of Longane Arillus was proven to have anxiolytic activity Okuyama et al. From our experiment, methanol extract of Longane Arillus was proven to prolong sleeping time and reduced pentobarbital-induced sleep onset in rodents through GABA A -ergic systems Ma et al. Methanol extract of Longane Arillus regulated sleep architectures and EEG power spectra in restraint-stressed rats Ma et al. Ginseng Panax ginseng , Araliaceae may be in part related to maintaining sleep and wakefulness, and alter EEG spectra of sleep-wake stage in mice Ma et al.

    Panax quinquefolium American ginseng were reported to have sleeping-modulating effects. Saponin fraction of Panax ginseng extract prolonged the duration of hexobarbital-induced sleep in mice Takagi et al. Majono-sides R2, a major saponin of Panax vietnamensis restored the hypnotic activity of pentobarbital, which was decreased by psychological stresses Nguyen et al. Ginsenoside Rg3-standarzied ginseng extract showed anti-stress effects and enhanced sleeping in restraint stressed animals Kim et al.

    There are evidences to suggest that the regulation of GABA A -ergic transmission is one of target for the sedative actions of ginseng Kimura et al. In human study, it has been confirmed that ginseng could improve the quality of sleep Han et al. EGCG EpigallocatechinO-gallate is a major component of green tea Camellia sinensis which is a popular beverage worldwide. However, green tea contains caffeine and EGCG. One is stimulant caffeine, and the other is EGCG which may be sedative.

    This may suggest that EGCG counteracts caffeine-induced stimulant effects such as hyperactivity, arousal and anxiogenic effects Park et al. The flower Chrysanthemum morifolium is a medicinal herb that has been used for tea preparation in oriental countries. Chrysanthemumsp contains flavonoids, phenols, cinnamic acids and on. The dry flower of Chrysanthemum morifolium in tea and pillow has been traditionally used for the treatment of insomnia in Korea.

    Apigenin from Circium japonicum , Asteraceae found in many plants, is a natural product belonging to flavonoids that are the aglycone of several naturally occurring glycosides. Apigenin is a weak ligand for central benzodiazepine receptors in vitro and exerts anxiolytic and slight sedative effects in an animal model Viola et al.

    Some natural products such as Polygalae Radix 3,4,5-trimethoxycinnamic acid , Gastrodiae Rhizoma 4-hydroxybenzaldehyde , Poria cocos pachymic acid , Rhychophilline Uncariae Ramulus et Uncus and Perilla Herba, were studied whether they enhance sleep or not Lee et al.

    From the behavioral and molecular data, those natural products augmented pentobarbital-induced sleep, and modulated sleep architectures of EEG spectra in rodents. Up to date, over the counter sleep aiding agents have been introduced. Natural products which have been proven to be effective for sleeping from our laboratory are reviewed.

    However, preclinical and clinical studies are needed to evaluate the precise effects of natural products for the treatment of insomnia. National Center for Biotechnology Information , U. Journal List Biomol Ther Seoul v. Published online Jun Author information Article notes Copyright and License information Disclaimer. Abstract Although drugs such as barbiturates and benzodiazepines are often used for the treatment of insomnia, they are associated with various side effects such as habituations, tolerance and addiction.

    Open in a separate window. Bioassay-guided fractionation of lemon balm Melissa officinalis L. A systematic review of regulatory and educational interventions to reduce the burden associated with the prescriptions of sedative-hypnotics in adults treated for sleep disorders. Anxiolytic-like effects of ginsenosides on the elevated plus-maze model in mice.

    Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, induces sleep via the benzodiazepine site of GABAA receptor in mice. Molecular determinants of resistance to antiandrogen therapy. Gastrodiae Rhizoma ethanol extract enhances pentobarbital-induced sleeping behaviors and rapid eye movement sleep via the activation of GABAA-ergic transmission in rodents. Evid Based Complement Alternat Med. Molecular targets for the myorelaxant action of diazepam.

    Melatonin with adenosine solubilized in water and stabilized with glycine for oncological treatment—technical preparation, effectivity and clinical findings. The epidemiology and diagnosis of insomnia. Am J Manag Care. Prescription drugs used in insomnia. Extracellular levels of serotonin and GABA in the hippocampus after chronic mild stress in rats.

    A microdialysis study in an animal model of depression. Anxiolytic-like effects of cyclopeptide fraction alkaloids of Zizyphi Spinosi semen: Biomol Ther Seoul ; Anxiolytic-like effects of sanjoinine A isolated from Zizyphi Spinosi Semen: Effects of red ginseng extract on sleeping behaviors in human volunteers. Reduction in synaptic GABA release contributes to target-selective elevation of PVN neuronal activity in rats with myocardial infarction.

    Differential pre- and postsynaptic mechanisms for synapic potentiation and depression between a granule cell and a purkinje cell in rat cerebellar culture.

    Natural Sleep Aids & Tips

    Ever wonder how to fall asleep faster at night? Here are 14 smart products and sleep aids to help you sleep better at night. If you're battling insomnia and desperately need some shut-eye, Netdoctor has come to the rescue with our lowdown of the best sleep inducing. Natural sleep aids are dietary and herbal supplements that can Nature Made is trusted to reliably source their products and ensure the.

    Read more tips, recipes, and insights on a wide variety of topics from Dr. Weil here.



    Comments

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